Andy Murray had to battle back from a set down to beat Spaniard Pablo Andujar in the opening round of the Abierto Mexicano Telcel in Acapulco.
Andujar, who held Rafael Nadal to match points in Rio de Janeiro a week ago, got off to another strong start as he took the first set and then broke Murray again, but the Scot responded by winning six games in a row on his way to a 3-6 6-1 6-2 victory.
Murray, making his first appearance in Latin America, will face Joao Sousa in the second round after the Portuguese saw off Adrian Mannarino 1-6 6-2 6-2.
Top seed David Ferrer, who won three straight titles in Acapulco from 2010 to 2012 when the tournament was played on clay, adjusted well to the new hard court as he breezed by Mikhail Kukushkin of Kazakhstan 6-2 6-3.
That has set up a second round meeting with Feliciano Lopez, with the Spaniard beating Edouard Roger-Vasselin of France 6-4 6-2.
Third seed John Isner is out already, having gone down 7-6 (7/4) 7-6 (7/5) to Ivo Karlovic, but there were no such problems for fifth seed Kevin Anderson, who beat French qualifier Stephane Robert 6-2 7-6 (9/7).
Seventh seed Ernests Gulbis dispatched Yen-Hsun Lu 6-1 6-1 while Alexandr Dolgopolov carried over his strong form from Rio by beating eighth seed Vasek Pospisil 6-2 6-2.
Fourth seed Grigor Dimitrov beat Australian Marinko Matosevic 7-5 6-1 and Gilles Simon advanced with a 6-1 6-2 win over Tim Smyczek.
Top seeds Dominika Cibulkova, Eugenie Bouchard and Kaia Kanepi advanced in the women's tournament but there was an early exit for number five Yvonne Meusburger.
Number one Cibulkova saw off Urszula Radwanska 6-3 6-4 while the second-seeded Bouchard was a 6-2 6-2 winner over Shahar Peer.
Third seed Kanepi had a little more work to do in a 6-1 3-6 6-2 win over Jana Cepelova, but Meusburger's tournament came to a premature end as qualifier Sharon Fichman enjoyed a straight-sets win, 6-1 6-3.
Eighth seed Shuai Zhang beat qualifier Madison Keys 4-6 6-1 6-4.
Yanina Wickmayer beat Lesia Tsurenko 7-6 (7/4) 6-4, and qualifier Victoria Duval advanced wit ha 6-2 6-4 win over Iveta Melzer.
Aleksandra Wozniak was given a tough test before beating qualifier Ashleigh Barty 7-6 (7/5) 5-7 6-2, but Julio Goerges was a convincing 6-0 6-1 winner over Marcela Zacarias.
Caroline Garcia beat Lourdes Dominguez Lino 6-4 7-6 (8/6) and Lara Arruabarrena saw off Galina Voskoboeva 6-2 6-4.