Amir Khan admitted facing unbeaten Colombian Breidis Prescott had been "a massive gamble" after a stunning 54-second knockout defeat left his world title dreams in tatters.

Khan, making his debut on pay-per-view, on Saturday night suffered the first loss of his professional career to dangerous puncher Prescott at the MEN Arena in Manchester.

"I just got caught with a big shot. That's boxing. I'll come back stronger," said Khan. "I knew he had speed and I knew he had power. It was a massive gamble taking this fight. I took it to see where I was and that happens, but I'll come back stronger."

Khan recently replaced trainer Oliver Harrison with Miami-based former Cuban Olympic coach Jorge Rubio, putting particular emphasis on improving his defence after being floored by Michael Gomez in his last fight and previously by Willie Limond and Rachid Drilzane.

And those new defensive tactics looked set to be immediately tested by the dangerous-looking Prescott, who arrived from Barranquilla with an unbeaten record of 17 knockouts in 19 wins - albeit against opponents of a questionable standard.

And Khan admitted he was well aware of his opponent's armoury and forgot his coach's advice when he needed it most.

"I knew exactly what was going on (after the first knockdown) but just ran onto the shot," Khan said.

"We worked on stuff in the gym and Jorge said not to do that, because he's a big hitter."